Characterization of central melatonin receptors using 125 I-melatonin
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چکیده
منابع مشابه
Ontogeny of central melatonin receptors in tadpoles of the anuran
11 Abstract The objective of this work was to study mela12 tonin receptors in the eye and the brain and their pos13 sible functionality in the ontogeny of Rana perezi. The 14 binding of 2-[I]melatonin increases throughout 15 embryonic larval development in both tissues. The most 16 pronounced increase takes place at the end of premeta17 morphosis and during early prometamorphosis. This 18 rise ...
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Melatonin receptors belong to the superfamily of G protein-coupled receptors. Cloning of Mel1c receptors expressed in Xenopus skin revealed the existence of a polymorphism for these receptors. Heterologous expression of the two allelic isoforms, called Mel1c(alpha) and Mel1c(beta), indicated functional differences in their signalling properties. Both isoforms are coupled to the cAMP and cGMP pa...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1986
ISSN: 0014-5793
DOI: 10.1016/0014-5793(86)80287-3